Analysis of mass-action systems by split network translation

We introduce the notion of corresponding a chemical reaction network to split translation, and use this novel process extend scope existing network-based theory for characterizing steady state set mass-action systems. In splitting, reactions are divided into subnetworks, called slices, in such way that, when summed across stoichiometry each sums that original network. This can produce with more desirable structural properties, as weak reversibility lower deficiency, which then be used establish properties system multistationarity absolute concentration robustness. also present computational implementation utilizing mixed-integer linear programming determining whether given has weakly reversible translation.